When Does a Difference Make a Difference? How to Figure Out What's Important in Clinical Trial Results

Thursday, September 7, 2023

1:30 PM – 2:45 PM CT

Location: 104 DE

Speaker(s)

Leslie Citrome, MD, MPH

Clinical Professor
Department of Psychiatry & Behavioral Sciences, New York Medical College, Valhalla, NY
New York Medical College

In this session, we will discuss the key concepts of statistical significance and clinical relevance in clinical trial results. You will gain an understanding of the difference between p-value and effect size, and how to calculate effect size. By the end of this session, you will have a clear understanding of the importance of these concepts in interpreting clinical trial results and be better equipped to differentiate between statistically significant results and those with clinical relevance. This session is essential for anyone involved in clinical research or who needs to interpret clinical trial results.

Learning Objectives:

Identify and understand absolute effect sizes such as number needed to treat and number needed to harm
Identify and understand relative effect sizes such as odds ratio, relative risk, and hazard ratio
Calculate simple effect sizes from information routinely presented about treatments